Publications

Peer-reviewed publications highlighting the research of our lab

Please feel free to contact us with questions about the lab’s publications.

Highlighted Publications

Radiogenomics of C9orf72 expansion carriers reveals global transposable element de-repression and enables prediction of thalamic atrophy and clinical impairment
Journal of Neuroscience
Bonham LW, Geier EGSirkis DW, Leong JK, Ramos EM, Wang Q, Karydas A, Lee SE, Sturm VE, Sawyer RP, Friedberg A, Ichida JK, Gitler AD, Sugrue L,  Cordingley M, Bee W, Weber E, Kramer J, Rankin KP, Rosen HJ, Boxer AL, Seeley WW, Ravits J, Miller BL, Yokoyama JS.

Dissecting the clinical heterogeneity of early-onset Alzheimer’s disease
Molecular Psychiatry
Sirkis DWBonham LWJohnson TP, La Joie R, Yokoyama JS.

Single-cell RNA-seq reveals alterations in peripheral CX3CR1 and nonclassical monocytes in familial tauopathy
Sirkis DW
Warly Solsberg CJohnson TPBonham LW, Sturm VE, Lee SL,  Katherine P. Rankin, Howard J. Rosen, Adam L. Boxer, William W. Seeley, Miller BL, Geier EGYokoyama JS.

Genetic, Social, and lifestyle drivers of health aging and longevity
Current Genetic Medicine Reports
Castruita PAPiña-Escudero SDRentería MEYokoyama JS.

Biomarkers for dementia in Latin American countries: Gaps and opportunities
Alzheimer’s and Dementia
Parra MA, Orellana P, Leon T, Victoria CG, Henriquez F, Gomez R, Avalos C, Damian A, Slachevsky A, Ibañez A, Zetterberg H, Tijms BM, Yokoyama JSPiña-Escudero SD, Cochran JN, Matallana DL, Acosta D, Allegri R, Arias-Suárez BP, Barra B, Behrens MS, Brucki SMD, Busatto G, Caramelli P, Castro-Suarez S, Contreras V, Custodio N, Dansilio S, De la Cruz-Puebla M, Cruz de Souza L, Diaz MM,  Duque,Gonzalo A. Farías,Sergio T. Ferreira,Guimet NH,Ana Kmaid,David Lira, Lopera F, Mar Meza B, Miotto EC, Nitrini R, Nuñez LA, O'Neill S, Ochoa J, Pintado-Caipa M, de Paula França Resende E, Risacher S, Rojas LA, Sabaj V,  Schilling L, Sellek AF, Sosa A, Takada LT, Teixeira AL, Unaucho-Pilalumbo M, Duran-Aniotz C.

Multimodal Neurocognitive Markers of Naturalistic Discourse Typify Diverse Neurodegenerative Diseases
Cerebral Cortex
Birba A, Fittipaldi S, Cediel Escobar JC, Gonzalez Campo C, Legaz, A Galiani A, Díaz Rivera MN, Martorell Caro M, Alifano F, Piña-Escudero SD,  Cardona, JF, Neely A, Forno G, Carpinella M, Slachevsky A, Serrano C, Sedeño L, Ibáñez A, García AM.

Dissecting the clinical heterogeneity of early-onset Alzheimer’s disease
Molecular Psychiatry
Sirkis DWBonham LWJohnson TP, La Joie R, Yokoyama JS.

Uremic Neuropathy Pain (book chapter)
Pain (Oxford Academic)
Piña-Escudero SD

Facilitators and Barriers to Dementia Assessment and Diagnosis: Perspectives From Dementia Experts Within a Global Health Context
Frontiers in Neurology
Bernstein Sideman A, Al-Rousan T, Tsoy E, Piña Escudero SD, Pintado-Caipa M, Kanjanapong S, Mbakile-Mahlanza L, Okada de Oliveira M, De la Cruz-Puebla M, Zygouris S, Ashour Mohamed A, Ibrahim H, Goode CA, Miller BL, Valcour V, Possin KL.

The severity of neuropsychiatric symptoms is higher in early-onset than late-onset Alzheimer's disease
European Journal of Neurology
Falgàs N, Allen IE, Spina S, Grant H, Piña Escudero SD, Merrilees J, Gearhart R, Rosen HJ, Kramer JH, Seeley WW, Neylan TC, Miller BL, Rabinovici GD, Grinberg LT, Walsh CM.

Non-coding and Loss-of-Function Coding Variants in TET2 are Associated with Multiple Neurodegenerative Diseases
American Journal of Human Genetics
Cochran JN, Geier EG, Bonham LW, Newberry JS, Amaral MD, Thompson ML, Lasseigne BN, Karydas AM, Roberson ED, Cooper GM, Rabinovici GD, Miller BL, Myers RM, Yokoyama JS.

The Transcriptional Landscape of Microglial Genes in Aging and Neurodegenerative Disease
Frontiers in Immunology
Bonham LW, Sirkis DWYokoyama JS.

Rare variants in the neuronal ceroid lipofuscinosis gene MFSD8 are candidate risk factors for frontotemporal dementia
Acta Neuropathologica
Geier EG, Bourdenx M, Storm NJ, Cochran JN, Sirkis DW, Hwang JH, Bonham LW, Ramos EM, Diaz A, Van Berlo V, Dokuru D, Nana AL, Karydas A, Balestra ME, Huang Y, Russo SP, Spina S, Grinberg LT, Seeley WW, Myers RM, Miller BL, Coppola G, Lee SE, Cuervo AM, Yokoyama JS.

Fine-mapping of the human leukocyte antigen locus as a risk factor for Alzheimer disease: A case-control study
PLOS Medicine
Steele NZ, Carr JS, Bonham LW, Geier EG, Damotte V, Miller ZA, Desikan RS, Boehme KL, Mukherjee S, Crane PK, Kauwe JS, Kramer JH, Miller BL, Coppola G, Hollenbach JA, Huang Y, Yokoyama JS.

Association Between Genetic Traits for Immune-Mediated Diseases and Alzheimer Disease
JAMA Neurology
Yokoyama JS, Wang Y, Schork AJ, Thompson WK, Karch CM, Cruchaga C, McEvoy LK, Witoelar A, Chen CH, Holland D, Brewer JB, Franke A, Dillon WP, Wilson DM, Mukherjee P, Hess CP, Miller Z, Bonham LW, Shen J, Rabinovici GD, Rosen HJ, Miller BL, Hyman BT, Schellenberg GD, Karlsen TH, Andreassen OA, Dale AM, Desikan RS.

 

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